🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

500 mg Serving Size
100 Servings
Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 500mg

Label Claims — Verification

All Other
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Organic Dairy Free

Product Information

📋 Directions for Use

Suggested use: Mix 500 mg into tea, juice, or your favorite smoothie.

⚠️ Warnings & Precautions

Not recommended for children.

🧪 Formulation Notes

Our water extraction and low-heat vacuum drying (wind dried, not spray dried) process preserves the natural nutrients & beneficial qualities of Berberis aristata with improved potency and bioavailability. 100% Berberis aristata

Certified organic and Star-K Kosher

Certified organic and Star-K Kosher

Water extracted & water soluble Better bioavailability and potency Vegetarian/vegan, non-GMO, non-irradiated

No additives, fillers, or other ingredients No petroleum solvents in the extraction No pesticides used growing the Berberis Vegetarian/vegan, non-GMO, non-irradiated

Vegetarian/vegan, non-GMO, non-irradiated

Certified organic by CCOF

No other ingredients added

Product of India 3rd party lab tested in USA

Additional Information

USDA Organic CCOF Certified Organic Star-K (Kosher)

Materia Organica primarily sells bulk ingredients to manufacturers and brand owners.

Product Code: BER30019

Store in sealed container in a dry, cool area.

Product Details

UPC / SKU BER30019-50g
DSLD Entry Date 2025-08-22
Product Type Botanical
Form Powder
DSLD ID 336964
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

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