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Acetyl-L-Carnitine 500 mg

product on market Capsule Thorne Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Acetyl-L-Carnitine is researched for its role in supporting mitochondrial function and cognitive health. There is moderate evidence suggesting it may assist with mental focus and energy metabolism. Current data indicates a high safety profile for most users at this dosage.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Acetyl-L-Carnitine 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (861 products) 61 studies (A:4, B:13)

Other Ingredients

Hypromellose Microcrystalline Cellulose Leucine Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 1 capsule two to three times daily or as recommended by your health-care practitioner.

Warnings & Precautions

Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Formulation Notes

Brain/Nerves

Gluten free

Additional Information

Store tightly sealed in a cool, dry place.

Manufactured in the USA using US & imported ingredients NSF Contents Certified

Metadata

Product Details

UPC / SKU6 93749 52002 3
DSLD Entry Date2025-06-25
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandThorne
DSLD ID336344
Data Updated2026-04-11
Research

Research Evidence

80
Research Sources
49
Avg Quality
43
Rct
14
Clinical Trial
11
Systematic Review
9
Meta Analysis
2
Regulatory Source
A Propionyl-L-carnitine for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Carnitine supplements for people with chronic kidney disease requiring dialysis
Systematic Review The Cochrane database of systematic reviews 2022 PubMed DOI
A Acetyl-L-carnitine for patients with hepatic encephalopathy
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
B Carnitine for fatigue in multiple sclerosis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B L-carnitine for cognitive enhancement in people without cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Carnitine for fatigue in multiple sclerosis
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Systematic Review and Meta-analysis on Effect of Carnitine, Coenzyme Q10 and Selenium on Pregnancy and Semen Parameters in Couples With Idiopathic Male Infertility
Meta Analysis Urology 2022 PubMed DOI
B Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis
Systematic Review Reproductive sciences (Thousand Oaks, Calif.) 2025 PubMed DOI
B Efficacy and Effectiveness of Carnitine Supplementation for Cancer-Related Fatigue: A Systematic Literature Review and Meta-Analysis
Meta Analysis Nutrients 2017 PubMed DOI
View all evidence for Carnitine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.