Home/ Supplements/ Berberine/ Berberine Plus

Berberine Plus

product on market Capsule True Botanica Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Berberine hydrochloride and barberry extracts are supported by moderate evidence for managing blood glucose levels and lipid profiles. Bioperine is included to enhance the bioavailability of these compounds. Overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Bioperine Nature's Thermonutrient
2 mg

Other Ingredients

Microcrystalline Cellulose Cellulose Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: Two capsules once or twice daily, or as suggested by your health care provider.

Warnings & Precautions

Consult your health care provider before using this product if you are pregnant, lactating or have other medical concerns or compatibility issues.

Do not use this product if allergies to the listed ingredients are known to exist or if any adverse effects result after taking the first dose.

This product contains a desiccant package, which should not be eaten.

Keep out of the reach of children.

Formulation Notes

A uniquely full spectrum berberine product. Contains all of the barberry herb's natural components, a high concentration of its main active ingredient berberine, plus the plant's natural salts and minerals. BioPerine included in order to further enhance bioavailability.

Contains no milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, sesame, or soybeans. Gluten free.

Vegetarian capsules.

Additional Information

Keep desiccant in the bottle until all capsules have been taken.

Metadata

Product Details

DSLD Entry Date2025-08-22
Product TypeOther Combinations
FormCapsule
DSLD ID336204
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
Compare

Similar Products

View all Berberine products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.