Home/ Supplements/ 5 Htp/ 5-HTP 50 mg

5-HTP 50 mg

product on market Capsule Country Life Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin and is supported by moderate evidence for aiding mood regulation and sleep quality. Research indicates it may help alleviate symptoms of depression and insomnia by increasing serotonin levels in the brain. Clinical data for these effects is generally considered promising but limited in long-term scope.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 50 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
50
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Cellulose Cellulose Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults take one (1) capsule daily with food or as directed by a health care professional.

Warnings & Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers. Caution: If you are pregnant, nursing, or taking medication, have a medical condition or planning surgery, consult a doctor before using this product.

Stop using and consult a doctor if any adverse reactions occur. Do not accept if seal is broken.

Keep out of the reach of children.

Formulation Notes

5-HTP is a natural conversion of the amino acid, L-tryptophan. It supports the production of serotonin in the brain.

Yes Certified Gluten-free by GFCO.org No Yeast, corn or wheat No soy or milk No salt or sugar No preservatives No artificial colors or flavors No artificial sweeteners

Yes Certified Vegan by the AVA

Yes Manufacturing supports wind power This product has been manufactured at a GMP Registered facility.

Yes Kosher-Parve

Yes Certified Halal by IFANICA

(5-Hydroxytryptophan)

Certified Gluten-Free

Supports serotonin production

Our Pledge of Integrity Authenticity Cleanliness Freshness Consistency Accuracy

Additional Information

Yes recyclable packaging

Certified B Corporation Certified GF Gluten-Free KOF-K (Kosher) Parve IFANCA Certified crescent M Halal

Store in a dry place between 59 degrees -86 degrees F.

Metadata

Product Details

UPC / SKU0 15794 01650 2
DSLD Entry Date2025-07-24
Product TypeAmino acid/Protein
FormCapsule
DSLD ID333169
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
Compare

Similar Products

View all 5 Htp products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.