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Waterex

product on market Capsule GNC Total Lean Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains Vitamin B6 and magnesium, which support metabolic function, alongside corn silk, fennel, and garlic. Research on these botanical ingredients for water reduction is limited. Overall, the evidence coverage for this specific ingredient profile is very low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Waterex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Botanical with Nutrients
Product Type
38%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

25 mg (1471% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
25 mg (6% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Corn Silk, Powder
6.25 mg
Fennel, Powder
6.25 mg
6.25 mg
Market median: 500.0mg (497 products) 135 studies (A:0, B:40)
Horsetail, Powder
6.25 mg
Parsley, Powder
6.25 mg
Uva-Ursi Leaf Extract
6.25 mg

Other Ingredients

Microcrystalline Cellulose Gelatin Potassium Chloride Calcium Silicate Cellulose Magnesium Stearate Maltodextrin Silicon Dioxide Sodium Lauryl Sulfate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take the contents of one pack daily. Do not take before bedtime.

Warnings & Precautions

Contains: Wheat. Contains a bioengineered food ingredient.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition.

Keep out of reach of children.

Formulation Notes

Advanced support as you strive to burn & define. Define your look. Get premium, clinically researched ingredients in just the right doses to support your nutrition and weight management goals - all in a convenient pack. WATEREX Featuring an all-natural herbal blend, this scientific formulation helps regulate water balance.

Scientifically Formulated Nutrition & Weight Management Support System Water balance with scientifically formulated Waterex

No Milk

Additional Information

Notice: Use in conjunction with the Total Lean Meal and Exercise Plan found on www.totallean.com.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you're not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days and we'll either refund your money or find a replacement product that is right for you. For more information: 1-888-462-2548 GNC.com

Store in a cool, dry place.

30-day supply

Metadata

Product Details

DSLD Entry Date2025-06-25
Product TypeBotanical with Nutrients
FormCapsule
BrandGNC Total Lean
DSLD ID330886
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.