90/100

This product looks safe

Contains proprietary blend — exact ingredient amounts not disclosed
Limited research evidence available for ingredients

B Label Compliance Grade

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Open Full PDF View on NIH DSLD →

Details

Label Data

1 Dropper(s)

Serving Size

Servings

Botanical

Product Type

Evidence Coverage

Ingredients

Supplement Facts — Evidence Check

Proprietary Blend

Other Ingredients

Grain Alcohol, Pure

Claims

Label Claims — Verification

Unverified All Other

Unverified Structure/Function

Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 1 dropperful 3 times a day, or as directed by your health care professional.

Additional Information

Store in a cool dry place.

Christopher's Original Formulas 1-800-453-1406 www.drchristopher.com John R. Christopher

Metadata

Product Details

UPC / SKU0 84783 49707 3

DSLD Entry Date2025-08-22

Product TypeBotanical

FormLiquid

BrandChristopher's Original Formulas

DSLD ID329265

Data Updated2026-04-11

Research

Research Evidence

Research Sources

Avg Quality

Systematic Review

Meta Analysis

Rct

Clinical Trial

Other

Narrative Review

Openfda Safety

B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials

Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI

B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI

B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2019 PubMed DOI

B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials

Meta Analysis The Journal of nutrition 2023 PubMed DOI

B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review

Meta Analysis Journal of translational medicine 2024 PubMed DOI

B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature

Systematic Review International journal of molecular sciences 2024 PubMed DOI

B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI

B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies

Meta Analysis International journal of molecular sciences 2023 PubMed DOI

B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial

Rct JAMA network open 2025 PubMed DOI

View all evidence for Berberine →

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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.