PalmettoGuard by Life Extension — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Softgel(s) Serving Size

30 Servings

Botanical with Nutrients Product Type

17% Evidence Coverage

Supplement Facts — Evidence Check

Calories

5 Calorie(s)

Total Fat

0.5 Gram(s) (1% DV)

Saw Palmetto fruit extract

320 mg

📊 Market median: 320.0mg (426 products) 📚 24 studies (Tier A: 0, B: 5)

This product: 320mg

Beta-Sitosterol

90 mg

Boron

3 mg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 3mg UL 20mg

Rosemary Leaf Extract

400 mcg

Other Ingredients

Pumpkin Seed Oil Gelatin Glycerin Sunflower Lecithin Water, Purified Caramel color

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (98% of products) Structure/Function (83% of products) Nutrient (17% of products)

Target Groups

Adult Male (18-50 Years) Seniors/Mature (>50 Years) - Men ONLY Gluten Free

Product Information

📋 Directions for Use

Directions: Take one (1) softgel daily, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Read the entire label and follow directions carefully prior to use.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

🧪 Formulation Notes

Saw Palmetto and Beta-Sitosterol

Promotes a healthy prostate

Gluten free Non GMO LE Certified

Additional Information

Scan for product info

Store tightly closed in a cool, dry place.

Non GMO LE Certified

Product Details

UPC / SKU 7 37870 17893 4

DSLD Entry Date 2025-03-25

Product Type Botanical with Nutrients

Form Softgel Capsule

Brand Life Extension

DSLD ID 328635

Data Updated 2026-04-11

Research Evidence

35 Research Sources

52 Avg Quality Score

15 Meta Analysis

11 Systematic Review

7 Rct

1 Narrative Review

1 Openfda Safety

B Serenoa repens for benign prostatic hyperplasia

Meta Analysis The Cochrane database of systematic reviews 2009

PubMed DOI

B Serenoa repens for benign prostatic hyperplasia

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI

B Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement: A systematic review and meta-analysis

Meta Analysis Investigative and clinical urology 2021

PubMed DOI

B Clinical Efficacy of Serenoa repens Versus Placebo Versus Alpha-blockers for the Treatment of Lower Urinary Tract Symptoms/Benign Prostatic Enlargement: A Systematic Review and Network Meta-analysis of Randomized Placebo-controlled Clinical Trials

Systematic Review European urology focus 2021

PubMed DOI

B Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene

Systematic Review European review for medical and pharmacological sciences 2019

PubMed DOI

B Comparison of Serenoa repens With Tamsulosin in the Treatment of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis

Meta Analysis American journal of men's health 2020

PubMed DOI

B Serenoa repens monotherapy for benign prostatic hyperplasia (BPH): an updated Cochrane systematic review

Systematic Review BJU international 2012

PubMed DOI

B Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis