Enhanced Sleep without Melatonin by Life Extension — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Vegetarian Capsule(s) Serving Size

30 Servings

Botanical with Nutrients Product Type

0% Evidence Coverage

Supplement Facts — Evidence Check

Proprietary Blend

200 mg

Casein Decapeptide

150 mg

Other Ingredients

Cellulose Microcrystalline Cellulose Maltodextrin Silica Stearate

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (86% of products) Nutrient (7% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule daily, or as recommended by a healthcare practitioner. May be taken during daytime for stress or before bed to help with sleep.

⚠️ Warnings & Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains milk (casein decapeptide)

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

🧪 Formulation Notes

Gluten Free Non GMO LE Certified

Sleep better, look better

Additional Information

Scan for product info

Store tightly closed in a cool, dry place.

Non GMO LE Certified

Product Details

UPC / SKU 7 37870 15113 5

DSLD Entry Date 2025-05-21

Product Type Botanical with Nutrients

Form Capsule

Brand Life Extension

DSLD ID 328446

Data Updated 2026-04-11

Research Evidence

291 Research Sources

55 Avg Quality Score

129 Meta Analysis

93 Systematic Review

51 Rct

11 Clinical Trial

2 Other

2 Regulatory Source

1 Openfda Safety

A Interventions for preventing delirium in hospitalised non-ICU patients

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed DOI

A Melatonin for preoperative and postoperative anxiety in adults

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI Cochrane

A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials

Meta Analysis BMJ open 2022

PubMed DOI

B Pharmacological interventions for prevention of weight gain in people with schizophrenia

Meta Analysis The Cochrane database of systematic reviews 2022

PubMed DOI

B Melatonin for pre- and postoperative anxiety in adults

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Prevention of depression in adults with long-term physical conditions

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis

Systematic Review Lancet (London, England) 2022

PubMed DOI

B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis

Meta Analysis BMJ open 2023

PubMed DOI

B Second-generation antidepressants for preventing seasonal affective disorder in adults

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

View all evidence for Melatonin →