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Melatonin

product on market Capsule Neurobiologix Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is a hormone that regulates sleep-wake cycles and is widely used to manage insomnia and jet lag. There is strong research evidence supporting its efficacy in reducing sleep onset latency. This ingredient is generally well-tolerated when used according to recommended dosages.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Methylcellulose Water Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Adults: 1 capsule daily as needed for sleep or as directed by a healthcare professional. Best taken in the evening. Children: As directed by a healthcare professional.

Warnings & Precautions

Caution: May cause drowsiness. Do not use melatonin while operating a motor vehicle or machinery.

Unless instructed by your physician, do not use melatonin if you have a seizure disorder, autoimmune disorder, endocrine disorder, or diabetes, or if you are pregnant, or trying to become pregnant, or are nursing, or if you are taking any medications.

Keep out of reach of children.

Do not use if shrinkwrap is broken or missing.

Keep out of reach of children.

In case of adverse reaction, call 866-500-8388

Professional use only

Formulation Notes

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.

Supports the sleep cycle

Additional Information

Store in a cool, dry place (59F-85F) away from direct light.

Metadata

Product Details

DSLD Entry Date2025-04-24
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID327682
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Melatonin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.