🟡 60/100

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  • Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

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Safety Alerts

⚠️ Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)

The safety score is low because the 20mg dose of melatonin in this product is twice the recommended upper limit of 10mg.

Label Data

1 Veg Capsule(s) Serving Size
90 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

20 mg
⚠️ Exceeds Tolerable Upper Intake Level by 2.0× (UL: 10 mg) 📚 236 studies (Tier A: 2, B: 109)
This product: 20mg UL 10mg

Other Ingredients

Magnesium Citrate Microcrystalline Cellulose Hypromellose Stearic Acid

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (7% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Halal Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested usage: Take 1 capsule prior to bedtime, or as directed by your healthcare practitioner. This product is not intended for long-term use. Use beyond 4 consecutive weeks should be only under the supervision of a healthcare practitioner.

⚠️ Warnings & Precautions

Cautions/interactions: This product is not intended for long-term use; use only as directed. May cause drowsiness. Do not operate a vehicle or heavy machinery following consumption of melatonin. Melatonin may interact with supplements such as St. John's Wort and 5-HTP.

Consult physician if pregnant/nursing, taking medication, especially sedatives, immunosuppressants or anticoagulants, or have a medical condition including diabetes, auto-immune conditions, depressive disorders, cardiovascular conditions and epilepsy.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

How it works: Melatonin is a potent free radical scavenger naturally produced in the pineal gland and the GI tract. It is involved in many of the regulatory processes of the body, including regulation of glandular secretory functions related to the maintenance of normal sleep/wake cycles, maintenance of GI health, and aspects of immune system function. Supplemental melatonin has been shown to support healthy sleep patterns especially when traveling across time zones or for shift workers.

Crescent H (Halal)

Healthy sleep cycle Supports gastrointestinal health

Non-GMO

Vegetarian/vegan

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

This Maximum Strength Melatonin 20 mg has twice the melatonin as in our Extra Strength 10 mg product.

Natural color variation may occur in this product.

Additional Information

Store in a cool, dry place after opening.

Crescent H (Halal)

Product Details

UPC / SKU 7 07359 13558 1
DSLD Entry Date 2025-03-25
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 326520
Data Updated 2026-04-11

Research Evidence

291 Research Sources
55 Avg Quality Score
129 Meta Analysis
93 Systematic Review
51 Rct
11 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021
View all evidence for Melatonin →

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