🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
110 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

2500 mcg (104167% DV)
📊 1041.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 2.5mg

Other Ingredients

Sucrose Mannitol Polyplasdone Crospovidone Hydroxypropyl Methylcellulose Magnesium Stearate Maltodextrin Cherry Flavor, Natural Silicon Dioxide Stearic Acid Sucralose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a vitamin supplement, adults take one (1) tablet daily with any meal or as directed by a healthcare provider. Place tablet under tongue for 30 seconds before swallowing. Do not exceed recommended dosage. Individual results may vary.

⚠️ Warnings & Precautions

Do not exceed recommended dosage. Stop use and contact a physician if adverse reactions occur.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

Quick dissolve Energy Support

Gluten free Non-GMO

Guaranteed quality Laboratory Tested Trusted Quality for over 30 years

No added salt, yeast, preservatives, artificial flavors or colors.

Vitamin B-12 (Cyanocobalamin) supports the body's nerves and blood cells. Quick dissolve Vitamin B-12 is a great tasting way to deliver your B vitamin.

Additional Information

Store at room temperature.

Product Details

UPC / SKU 7 40985 27112 4
DSLD Entry Date 2025-01-23
Product Type Vitamin
Form Tablet or Pill
Brand 21st Century
DSLD ID 326312
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

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