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Glucosamine 500 mg

product on market Tablet or Pill The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Regenasure D-Glucosamine HCl is used to support joint health and cartilage maintenance. Clinical evidence for its efficacy in reducing joint discomfort is generally considered moderate. This ingredient profile maintains a high safety score for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate purified Water Hydroxypropyl Methylcellulose Polyethylene Glycol
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: As a dietary supplement, take one (1) tablet three (3) times daily, preferably with meals.

Warnings & Precautions

Consult your physician prior to use if you are diabetic.

KEEP OUT OF REACH OF CHILDREN.

TAMPER EVIDENT Do not use if outer seal is broken or missing.

WARNING: Do not take if you are pregnant or nursing.

Not to be taken by children.

Formulation Notes

vegetarian source and shellfish free

vegetarian source and shellfish free

gluten free dairy free soy free nut free

Does not contain: Yeast, Wheat, Gluten, Sugar, Salt, Soy, Dairy, Citrus, Fish, Animal Derivatives, Preservatives, Artificial Colors or Flavors.

Additional Information

Item No. VS-1965 1618156 AO 1

joint

STORE IN A COOL, DRY PLACE.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

specialty

{tablet} actual size

V SUITABLE FOR MOST VEGETARIANS

Metadata

Product Details

UPC / SKU7 66536 01965 6
DSLD Entry Date2014-04-25
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
DSLD ID32554
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.