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5-HTP Pure 100 mg

product on market Capsule Pure Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

L-5-Hydroxytryptophan is used to support serotonin levels, with moderate evidence suggesting its role in mood regulation. Calcium is an essential mineral necessary for bone health and cellular signaling. Overall, clinical evidence for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP Pure 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Amino acid/Protein
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
128 mg (13% DV)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Dicalcium Phosphate Gelatin Silica Cellulose Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, adults take two (2) capsules once daily as needed or at bedtime as 5-HTP may produce drowsiness, or as directed by a healthcare professional.

Warnings & Precautions

Caution: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Do not drive, operate machinery or consume alcohol when taking this product. Keep out of reach children, do not use if safety seal is damaged or missing, store in a cool, dry place

Not intended for use by persons under the age of 18. Keep out of reach children, do not use if safety seal is damaged or missing, store in a cool, dry place.

Formulation Notes

Natural sleep aid Helps regulate sleep cycle Supports appetite control Replenishing serotonin levels to support positive mood.

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish. Sodium free.

Additional Information

Keep out of reach children, do not use if safety seal is damaged or missing, store in a cool, dry place

Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured Made in USA

Metadata

Product Details

UPC / SKU8 19070 01263 5
DSLD Entry Date2025-03-25
Product TypeAmino acid/Protein
FormCapsule
DSLD ID323829
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.