🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
90 Servings
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

5 mg (294% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
50 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 50mg

Other Ingredients

Microcrystalline Cellulose Hypromellose Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement, take 1 capsule 20 minutes before a meal, three times daily, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: If pregnant, nursing or taking MAO inhibitors, anti-depressants or being treated for Parkinson's Disease, consult your healthcare practitioner before taking this product.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776.

🧪 Formulation Notes

Color of this product may vary due to color variations of the natural ingredients.

A Dietary Supplement to Support Proper Mood and Sleep

Vegetarian

Gluten free

Additional Information

Truth We pledge total truth in labeling. Our family of products contains only the purest and most potent ingredients. Guaranteed.

Store in a cool, dry place.

Product Details

UPC / SKU 0 26664 22829 1
DSLD Entry Date 2025-01-23
Product Type Other Combinations
Form Capsule
DSLD ID 322146
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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