🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
90 Servings
Other Combinations Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 500mg
Enzyme Blend
21.5 mg
Trace Mineral
5 mg

Other Ingredients

Rice Extract Cellulose Water

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take 1 capsule with each meal, or within 30 minutes of eating a meal.

⚠️ Warnings & Precautions

Caution: Keep out of reach of children.

Do not use if ulcer or gastritis are present. As with any product, discontinue immediately if adverse effects occur. Please consult a physician before beginning any new supplement, diet, training program, or if you are undergoing treatment of a medical condition.

🧪 Formulation Notes

HCL Breakthrough is a natural source of beet-derived hydrochloric acid, that may help increase stomach acid, or hydrochloric acid to support digestion and detoxification.

Optimized digestive solutions

Vegan

Gluten-free Soy-free

Natural digestive support

Additional Information

Store in a cool/dry location.

To reorder or contact us, please visit: BiOptimizers.com

Product Details

UPC / SKU 0 648620 408426
DSLD Entry Date 2024-11-22
Product Type Other Combinations
Form Capsule
Brand BiOptimizers
DSLD ID 320984
Data Updated 2026-04-11

Research Evidence

849 Research Sources
56 Avg Quality Score
450 Meta Analysis
152 Rct
137 Systematic Review
73 Clinical Trial
11 Regulatory Source
7 Other
7 Guideline
3 Openfda Safety
2 Cochrane Review
2 Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021
View all evidence for Electrolytes →

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