100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
Limited research evidence available for ingredients

B Label Compliance Grade

Label

Product Label

Open Full PDF View on NIH DSLD →

Details

Label Data

2 Capsule(s)

Serving Size

Servings

Non-Nutrient/Non-Botanical

Product Type

Evidence Coverage

Ingredients

Supplement Facts — Evidence Check

Hyaluronic Acid

100 mg

Market median: 100.0mg (173 products)

Other Ingredients

Rice Extract Gelatin

Claims

Label Claims — Verification

Unverified All Other

Unverified Structure/Function

Info

Product Information

Directions for Use

Dosage: Take 2 capsules daily at bedtime.

Warnings & Precautions

Warning: Keep out of the reach of children and consult with a physician before taking this product if you are pregnant, nursing or have a medical condition.

Formulation Notes

Extracellular matrix

H.A.95 naturally occurring rooster comb hyaluronic acid has negatively charged compounds with high viscosity known as N-Acetylglucosamine and Glucuronic Acid (amino sugars). Hyaluronic acid works in synergy with collagen type I, II, III, V, & X. It also aids as a natural constituent for joints, skin matrix, eyes and wound healing.

Soy Free Gluten Free GMO Free

Connective tissue & cellular hydration Nutraceuticals from nature

Natural rooster comb Nutritive food grade polysaccharides 95% naturally occurring hyaluronic acid

Cellular Hydration

Metadata

Product Details

UPC / SKU8 57549 00214 5

DSLD Entry Date2025-01-23

Product TypeNon-Nutrient/Non-Botanical

FormCapsule

BrandLongevity by Nature

DSLD ID320949

Data Updated2026-04-11

Research

Research Evidence

Research Sources

Avg Quality

Rct

Clinical Trial

Systematic Review

Guideline

B Dressings and topical agents containing hyaluronic acid for chronic wound healing

Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI

B Effect of laughter exercise versus 0.1% sodium hyaluronic acid on ocular surface discomfort in dry eye disease: non-inferiority randomised controlled trial

Rct BMJ (Clinical research ed.) 2024 PubMed DOI

B Expert consensus on hyaluronic acid injections for knee osteoarthritis: a patient-centered approach.

Guideline Aging clinical and experimental research 2026 PubMed DOI

C The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial

Rct Nutrients 2024 PubMed DOI

C Effects of ozone combined with articular injection of sodium hyaluronate on patients with knee osteoarthritis and their inflammatory factors and hemorheological indices.

Rct African health sciences PubMed DOI

C The effect of oral low molecular weight liquid hyaluronic acid combination with glucosamine and chondroitin on knee osteoarthritis patients with mild knee pain: An 8-week randomized double-blind placebo-controlled trial.

Rct Medicine PubMed DOI

C Liquid combination of hyaluronan, glucosamine, and chondroitin as a dietary supplement for knee osteoarthritis patients with moderate knee pain: A randomized controlled study.

Rct Medicine PubMed DOI

C Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial.

Rct The journal of sexual medicine PubMed DOI

C PMCF Study to Evaluate Performance and Safety of 'Hyaluronic Acid (HA)-Based Eyedrops' Used to Relieve Dry Eye Symptoms

Clinical Trial ClinicalTrials.gov 2022

C Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections

Clinical Trial ClinicalTrials.gov 2022

View all evidence for Hyaluronic Acid →

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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.