🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

1000 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 1000mg

Other Ingredients

Hypromellose Hydroxypropylmethylcellulose Monolaurin Microcrystalline Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Recommended use: As a dietary supplement, take 1-2 capsules, one to two times per day, or as recommended by a healthcare professional.

⚠️ Warnings & Precautions

Warning: Consult with a health care professional before use and/or if you are pregnant, lactating, or undergoing treatment for a medical condition.

Do not exceed recommended dosage. Discontinue use if any adverse reactions occur and contact a health care professional. Do not use if seal under cap is broken or missing.

Keep out of reach of children.

🧪 Formulation Notes

Berberine is a powerful, natural plant alkaloid shown to help regulate blood glucose and cholesterol levels already in normal range, and modulate adipose tissue which can support metabolic health.

Gluten Free BPA free

Purity Potency Tested

Contains no milk, soy, egg, fish, peanuts, crustacean shellfish, tree nuts, wheat, gluten, rice, or yeast. No artificial colors or flavors. No toxic fillers, including stearates and palmitates.

Lab tested for contaminants, including heavy metals and mold. Unlike most enteric coatings, our capsules do not contain plastic phthalates.

Amber glass bottles eliminate leaching of toxins into our bodies and planet.

Additional Information

Store tightly closed in a cool, dry place.

Made in the USA from Global Ingredients Manufactured by a GMP Certified Company

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Product Details

UPC / SKU 8 97395 00286 2
DSLD Entry Date 2025-03-25
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 320614
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

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