🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
360 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
30 mg (33% DV)
120 mg (28% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 120mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 250mg

Other Ingredients

Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Use Consume one capsule three times daily-preferably with food. You can increase or decrease your intake as required or as guided by your physician. There is no need to consume more than six capsules daily. For questions about the use of this product call 800.800.1200.

🧪 Formulation Notes

Since 1979, Unsurpassed purity, quality and efficacy. 100% Solar production Zero-carbon footprint 100% Solar

Barberry Root Extract

Blood sugar balance Cholesterol support

Berberine 250 provides a standardized extract of berberine from the root of the barberry plant. It is intended for those seeking to naturally support healthy blood sugar and cholesterol metabolism. Like turmeric, berberine's bright yellow color has made it a popular natural coloring agent throughout Asia for thousands of years. Also like turmeric, berberine has been respected for centuries as an important traditional medicine. Modern science and research have validated the wisdom of many traditional medical practices, including the use of berberine. Among its many beneficial properties, researchers have studied berberine's ability to naturally promote healthy blood sugar balance and metabolism while also promoting healthy blood lipid and cholesterol metabolism. As a society, our expanding waistlines have only increased our concerns regarding blood sugar and cholesterol. Our berberine extract provides a natural means of supporting our efforts toward more balanced blood sugar, lipids and cholesterol.

Contains no milk, soy, yeast, corn, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens, genetically modified (GMO) ingredients or manufacturing additives.

Additional Information

Questions? Reorders? 800.800.1200 procaps.com Andrew Lessman

Product Details

UPC / SKU 460163
DSLD Entry Date 2025-01-23
Product Type Other Combinations
Form Capsule
DSLD ID 320061
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

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