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Berberine 250

product on market Capsule ProCaps Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Berberine hydrochloride has moderate evidence for supporting glycemic control and metabolic health. Vitamin C and magnesium are well-established nutrients that support immune function and muscle relaxation. Collectively, these ingredients provide a combination of metabolic and general wellness support based on existing research.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine 250
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
360
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
30 mg (33% DV)
120 mg (28% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)

Other Ingredients

Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use Consume one capsule three times daily-preferably with food. You can increase or decrease your intake as required or as guided by your physician. There is no need to consume more than six capsules daily. For questions about the use of this product call 800.800.1200.

Formulation Notes

Since 1979, Unsurpassed purity, quality and efficacy. 100% Solar production Zero-carbon footprint 100% Solar

Barberry Root Extract

Blood sugar balance Cholesterol support

Berberine 250 provides a standardized extract of berberine from the root of the barberry plant. It is intended for those seeking to naturally support healthy blood sugar and cholesterol metabolism. Like turmeric, berberine's bright yellow color has made it a popular natural coloring agent throughout Asia for thousands of years. Also like turmeric, berberine has been respected for centuries as an important traditional medicine. Modern science and research have validated the wisdom of many traditional medical practices, including the use of berberine. Among its many beneficial properties, researchers have studied berberine's ability to naturally promote healthy blood sugar balance and metabolism while also promoting healthy blood lipid and cholesterol metabolism. As a society, our expanding waistlines have only increased our concerns regarding blood sugar and cholesterol. Our berberine extract provides a natural means of supporting our efforts toward more balanced blood sugar, lipids and cholesterol.

Contains no milk, soy, yeast, corn, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens, genetically modified (GMO) ingredients or manufacturing additives.

Additional Information

Questions? Reorders? 800.800.1200 procaps.com Andrew Lessman

Metadata

Product Details

UPC / SKU460163
DSLD Entry Date2025-01-23
Product TypeOther Combinations
FormCapsule
DSLD ID320061
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.