Home/ Supplements/ 5 Htp/ 5-HTP 100 mg

5-HTP 100 mg

product on market Capsule ProCaps Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

5-HTP is a precursor to serotonin with moderate evidence supporting its role in mood regulation. Calcium and magnesium are essential minerals that support neuromuscular function and bone health. Research for these combined ingredients is well-established, though the specific formulation's evidence coverage is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
240
Servings
Non-Nutrient/Non-Botanical
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
50 mg (4% DV)
20 mg (5% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Gelatin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use Consume one capsule daily. You can increase your intake as required or as guided by your physician.

Warnings & Precautions

Warning Not for use if you are pregnant or lactating, driving a motor vehicle, operating machinery or using sedative or antidepressant drugs. Discontinue use at least two days before any procedure requiring general anesthesia.

If you are under a physician's care, seek their advice before using this product.

Formulation Notes

Since 1979, Unsurpassed purity, quality, and efficacy.

100% Solar

5-Hydroxytryptophan Natural Griffonia Simplicifolia

5-HTP 100 provides a concentrated natural source of the amino acid, 5-hydroxytryptophan (5-HTP) from Griffonia simplicifolia seed. 5-HTP is a metabolic intermediate of the essential amino acid tryptophan and is the immediate precursor to the important neurotransmitter serotonin. As a result, 5-HTP plays an essential role in our body's synthesis of serotonin, which helps to enhance sleep quality while also promoting positive mood and supporting digestive system function and appetite control. Serotonin levels have been shown to be associated with the regulation of sleep, mood, appetite and the digestive process, which makes supplementing 5-HTP an important means of supporting these essential functions. Clinical research has shown that 5-HTP has the ability to cross the blood-brain barrier providing a direct means of promoting serotonin production and its benefits. Furthermore, 5-HTP also supports melatonin synthesis, which helps to regulate normal sleep schedule and may enhance sleep quality. 5-HTP can also promote healthy levels of other essential neurotransmitters and other neurochemicals, including dopamine and norepinephrine. In short, 5-HTP 100 is a simple, natural means of supporting the brain and healthy neurochemistry, along with sleep, mood and even digestive function.

Contains no additives or common allergens

Contains no milk, soy, yeast, corn, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens, genetically modified (GMO) ingredients or manufacturing additives.

Additional Information

For questions about the use of this product call 800.800.1200.

Questions? Reorders? 800.800.1200 procaps.com Andrew Lessman

Metadata

Product Details

UPC / SKU727821
DSLD Entry Date2024-12-21
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID320052
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
Compare

Similar Products

View all 5 Htp products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.