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Perna Plus

product on market Tablet or Pill DaVinci Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine sulfate, MSM, and green-lipped mussel extract are commonly used to support joint health, though clinical evidence for their efficacy remains moderate. Manganese and N,N-Dimethylglycine HCl provide additional metabolic and connective tissue support. Overall, the evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Perna Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
90
Servings
Other Combinations
Product Type
20%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (435% DV)
4.3× RDA — above typical dose (UL: 11 mg) 9 studies — no high-quality reviews
Green-Lipped Mussel Extract
1000 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
MSM
400 mg
Market median: 1000.0mg (2 products)
N,N-Dimethylglycine HCl
200 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Stearate Sodium Carboxymethycellulose Silicon Dioxide Cinnamon oil Polyethylene Glycol Methylcellulose Titanium Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, take 2 tablets, 3 times daily with food for 2 to 4 weeks, then reduce to 2 tablets once or twice daily with food, or as directed by your healthcare practitioner.

Warnings & Precautions

Warning: If pregnant or nursing, consult your healthcare practitioner before taking this product.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776. Not labeled for sale in California

Contains: Crustacean shellfish (shrimp & crab).

Formulation Notes

The effectiveness of Perna Plus is due to the unique biological activity of the many identified nutrients in the Perna mussel combined with Glucosamine, DMG, and Methylsulfonylmethane.

A dietary supplement to support proper joint and connective tissue functions

Gluten free

Additional Information

Truth We pledge total truth in labeling. Our family of products contains only the purest and most potent ingredients. Guaranteed.

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 26664 23651 7
DSLD Entry Date2024-09-25
Product TypeOther Combinations
FormTablet or Pill
BrandDaVinci Laboratories
DSLD ID318975
Data Updated2026-04-11
Research

Research Evidence

11
Research Sources
47
Avg Quality
7
Rct
2
Meta Analysis
1
Regulatory Source
C Trace elements and Alzheimer dementia in population-based studies: A bibliometric and meta-analysis
Meta Analysis Environmental pollution (Barking, Essex : 1987) 2023 PubMed DOI
C Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone
Rct Journal of animal science 2010 PubMed DOI
C Reducing mineral usage in feedlot diets for Nellore cattle: II. Impacts of calcium, phosphorus, copper, manganese, and zinc contents on intake, performance, and liver and bone status
Rct Journal of animal science 2017 PubMed DOI
C Copper, Ceruloplasmin, Zinc, and Manganese Levels in Brain and Biological Fluids from Parkinson's Disease Patients: Systematic Review and Meta-Analysis
Meta Analysis Cells 2026 PubMed DOI
C Risedronate reverses bone loss in postmenopausal women with low bone mass: results from a multinational, double-blind, placebo-controlled trial. BMD-MN Study Group
Rct The Journal of clinical endocrinology and metabolism 2000 PubMed
C Dietary Reference Intakes: Manganese
Regulatory Source IOM/NAM Dietary Reference Intakes 2000
C Vitamins and minerals intake adequacy in hematopoietic stem cell transplant: results of a randomized controlled trial.
Rct Bone marrow transplantation PubMed DOI
C Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain.
Rct Endocrine, metabolic & immune disorders drug targets PubMed DOI
C Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study
Rct Military medicine 1999 PubMed
C Effects of a cream containing madecassoside, 5% panthenol, and copper-zinc-manganese on improving postlaser resurfacing wound healing: A split-face, randomized trial.
Rct Dermatologic therapy PubMed DOI
View all evidence for Manganese →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.