🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
200 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

1000 mcg (41666% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg

Other Ingredients

Dicalcium Phosphate Mannitol Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide Stearic Acid

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

As a dietary supplement, take one (1) tablet daily preferably with a meal or as directed by a healthcare professional.

Directions: Take one (1) tablet daily preferably with a meal or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Caution Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur. Do not use if safety seal is damaged or missing.

Keep out of reach of children.

🧪 Formulation Notes

Vitamin B-12 (as cyanocobalamin) is an essential vitamin for energy. Vitamin B-12 provides support and stimulates nervous system functions and helps convert food into cellular energy.

Non GMO Gluten free

Energy support Promotes energy Supports nervous system function Helps convert food into cellular energy Made in USA

Vegan

No: milk, egg, fish, crustacean shellfish, tree nuts, peanuts, yeast, artificial colors, flavors or preservatives.

Additional Information

Storage Store at room temperature 59 - 86 degrees F (15 - 30 degrees C) Keep bottle tightly closed.

Made in the USA

Value size

Store in a cool, dry place.

Questions or comments? Call 1-844-384-3723 9 AM - 5 PM Monday - Friday

Product Details

UPC / SKU 8 50012 52099 3
DSLD Entry Date 2024-09-25
Product Type Vitamin
Form Tablet or Pill
Brand Safrel
DSLD ID 318397
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

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