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D3 50,000 IU 1,250 mcg

product on market Capsule Safrel Safety: 60/100
60/100

Review before taking

  • Vitamin D3: 1.25mg is 12.5× the Tolerable Upper Intake Level (0.1mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin D3 is supported by strong evidence for maintaining bone health and supporting immune function. However, the high dosage of 50,000 IU may pose safety concerns regarding toxicity or hypercalcemia. Users should exercise caution due to the potential for vitamin D overdose.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D3: 1.25mg is 12.5× the Tolerable Upper Intake Level (0.1mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains a dose of Vitamin D3 that is 12.5 times higher than the recommended upper limit for daily intake.

Label

Product Label

Label for D3 50,000 IU 1,250 mcg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
120
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1250 mcg (6250% DV)
Exceeds UL by 12.5× (UL: 0.1 mg) 608 studies (A:16, B:251)

Other Ingredients

Cellulose Silicon Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Once weekly

Suggested use: Take one (1) capsule once weekly, preferably with food.

Warnings & Precautions

Warning: Consult your doctor if you are pregnant, nursing, taking any medications or have a medical condition.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

Vitamin D3 or cholecalciferol, which is the same type of vitamin D your body makes when exposed to sunlight and it is also the version used to fortify foods. Vitamin D is important for optimal bone, cardiovascular, neuromuscular

Made in U.S.A.

Vegan

Non GMO Gluten free

Immune support Bone health

No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, yeast.

Additional Information

Store at room temperature.

Metadata

Product Details

UPC / SKU8 50012 52083 2
DSLD Entry Date2024-08-22
Product TypeVitamin
FormCapsule
BrandSafrel
DSLD ID318388
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.