🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
120 Servings
Mineral Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

241.3 mg (60% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 241.3mg

Other Ingredients

Croscarmellose Sodium Hypromellose Microcrystalline Cellulose Silicon Dioxide Stearic Acid

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (78% of products) Nutrient (46% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Antacid Directions: Adults: Take one (1) tablet twice day or as directed by a physician. Magnesium Supplement Directions: Adults: Take one (1) or two (2) tablets daily or as directed by a physician.

⚠️ Warnings & Precautions

Drug Interaction Precaution: This product may interact with certain prescription drugs. If you are presently taking a prescription drug, do not take this product without consulting your doctor or other health professional. Ask a doctor or pharmacist before use if you are taking a prescription drug. Antacids may interact with certain prescription drugs. If pregnant or breast-feeding, ask a health professional before use.

Warning: Ask a doctor if you have kidney disease. Do not take more than 2 tablets in a 24 hour period or use the maximum dosage of this product for more than two weeks, except under the advise and supervision of a physician. Do not use if seal under cap is broken or missing

Keep out of reach of children.

🧪 Formulation Notes

Pharmaceutical grade Helps: Acid indigestion & upset stomach Muscle and nerve function Normal heart rhythm & blood pressure Absorption of calcium & potassium

241.3mg of Elemental Magnesium

No: milk, egg, fish, crustacean shellfish, tree nuts, peanuts, yeast, artificial colors, flavors or preservatives. Non-GMO Gluten free

Made in USA

Additional Information

Storage: Store at controlled room temperature 59 Degrees - 86 Degrees F (15 Degrees - 30 Degrees C). Keep bottle tightly closed.

NDC 71309-583-12

Questions or comments? Call 1-844-384-3723

Product Details

UPC / SKU 3 71309 58312 0
DSLD Entry Date 2024-09-25
Product Type Mineral
Form Tablet or Pill
Brand Safrel
DSLD ID 318383
Data Updated 2026-04-11

Research Evidence

7 Research Sources
45 Avg Quality Score
6 Rct
1 Meta Analysis
C Effectiveness and safety of polyethylene-glycol-4000 versus sodium picosulphate plus magnesium oxide and citric acid for bowel cleansing before colonoscopy in children: A systematic review with meta-analysis
Meta Analysis Journal of pediatric gastroenterology and nutrition 2025
C A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls
Rct The Journal of clinical endocrinology and metabolism 2006
C Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial
Rct The American journal of gastroenterology 2021
C The efficacy of magnesium oxide and sodium valproate in prevention of migraine headache: a randomized, controlled, double-blind, crossover study.
Rct Acta neurologica Belgica
C A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Rct Nutrition journal
C Comparative study between manitol and sodium picosulfate with magnesium oxide solutions in the preparation for colonoscopy.
Rct Revista do Colegio Brasileiro de Cirurgioes
C Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
Rct Magnesium research
View all evidence for Magnesium Oxide →

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