🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 20% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Caplet(s) Serving Size
60 Servings
Botanical with Nutrients Product Type
20% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Calcium
94 mg (7% DV)
72 mg (6% DV)
✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 72mg UL 4000mg
📊 Market median: 285.0mg (90 products) 📚 1 studies — no high-quality reviews
This product: 300mg
Proprietary Herbal Blend
200 mg

Other Ingredients

Dicalcium Phosphate Cellulose Stearic Acid Acacia Gum Maltodextrin Palm Leaf Glaze Silica Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: for adults, take one (1) caplet in the morning and one (1) in the evening, preferably with meals.

⚠️ Warnings & Precautions

Warning: not intended for use by pregnant or nursing women. If you are taking any medications, including blood thinners, planning any medical or surgical procedure have any medical condition, consult your doctor before use.

Avoid this product if you have liver or kidney disease. Discontinue use and consult your doctor if any adverse reactions occur. Do not use if seal under cap is broken or missing.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Contains bioengineered food ingredients.

🧪 Formulation Notes

The seeds of the Horse Chestnut tree contain a biologically active compound called aescin. As an active ingredient, aescin helps promote healthy circulation and fluid balance in the legs.

Supports healthy circulation & fluid balance in the legs

Additional Information

Store at room temperature.

To reorder item # 5545 www.puritan.com 1-800-645-1030

QA Quality Assured

Product Details

UPC / SKU 0 74312 15545 1
DSLD Entry Date 2024-08-22
Product Type Botanical with Nutrients
Form Other (e.g. tea bag)
DSLD ID 318223
Data Updated 2026-04-11

Research Evidence

849 Research Sources
56 Avg Quality Score
450 Meta Analysis
152 Rct
137 Systematic Review
73 Clinical Trial
11 Regulatory Source
7 Other
7 Guideline
3 Openfda Safety
2 Cochrane Review
2 Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021
View all evidence for Electrolytes →

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