Home/ Supplements/ Electrolytes/ Timed Release Circuleg

Timed Release Circuleg

product on market Other (e.g. tea bag) Puritan's Pride Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 20% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Horse chestnut seed extract has moderate evidence for supporting venous health and reducing leg swelling. Other components, including calcium and phosphorus, provide basic mineral support. Overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Timed Release Circuleg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
20%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Calcium
94 mg (7% DV)
72 mg (6% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
Market median: 285.0mg (90 products) 1 studies — no high-quality reviews
Proprietary Herbal Blend
200 mg

Other Ingredients

Dicalcium Phosphate Cellulose Stearic Acid Acacia Gum Maltodextrin Palm Leaf Glaze Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: for adults, take one (1) caplet in the morning and one (1) in the evening, preferably with meals.

Warnings & Precautions

Warning: not intended for use by pregnant or nursing women. If you are taking any medications, including blood thinners, planning any medical or surgical procedure have any medical condition, consult your doctor before use.

Avoid this product if you have liver or kidney disease. Discontinue use and consult your doctor if any adverse reactions occur. Do not use if seal under cap is broken or missing.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Contains bioengineered food ingredients.

Formulation Notes

The seeds of the Horse Chestnut tree contain a biologically active compound called aescin. As an active ingredient, aescin helps promote healthy circulation and fluid balance in the legs.

Supports healthy circulation & fluid balance in the legs

Additional Information

Store at room temperature.

To reorder item # 5545 www.puritan.com 1-800-645-1030

QA Quality Assured

Metadata

Product Details

UPC / SKU0 74312 15545 1
DSLD Entry Date2024-08-22
Product TypeBotanical with Nutrients
FormOther (e.g. tea bag)
DSLD ID318223
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.