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Milk Thistle

product on market Capsule Kirkman Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Milk thistle fruit extract is associated with liver support, though clinical evidence is often considered limited or mixed. Calcium and phosphorus are essential minerals that support bone health and cellular function. Research for these ingredients is generally well-established, though the overall evidence coverage for this specific formulation is low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
100
Servings
Botanical with Nutrients
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
45 mg (3% DV)
35 mg (3% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Hypromellose Water Silicon Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take one to two capsules daily or as directed by a physician.

Warnings & Precautions

Keep out of the reach of children. Caution: Formulated for adults and children four years and older. For children under four, consult a physician.

Formulation Notes

Free of: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame

Hypoallergenic

Gluten-free

Supports healthy liver function

Additional Information

Important: Store in a cool dry place and tightly capped.

Ultra tested cGMP

503.694.1600

Metadata

Product Details

UPC / SKU8 12325 02049 2
DSLD Entry Date2024-08-22
Product TypeBotanical with Nutrients
FormCapsule
BrandKirkman
DSLD ID317761
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.