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Berberine HCl Complex

product on market Capsule ForestLeaf Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Berberine HCl is supported by strong evidence for its role in managing blood glucose levels and improving metabolic health. The accompanying botanical complex provides complementary support, though specific evidence for this blend is more limited. The formulation maintains a high safety profile for general use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine HCl Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
45
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Premium Botanical Complex
300 mg

Other Ingredients

Hypromellose Magnesium Stearate Silicon Dioxide Microcrystalline Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, adults take 2 capsules once to twice daily, preferably with food, or as directed by your healthcare professional.

Warnings & Precautions

Caution: Keep out of reach of children.

If you are pregnant, nursing, or taking any prescription medicine, consult your physician before taking this product.

Formulation Notes

At ForestLeaf, our mission is to provide high-quality supplements that support health and wellness. We believe that nature provides us with everything we need to thrive. At ForestLeaf, we are committed to helping you live your best life. ForestLeaf: Health focused Quality committed Research driven Made in USA with globally sourced ingredients GMP compliant Lab verified

Vegetarian friendly

Non GMO Dairy, gluten, egg & nut free

Pure formula 97% Advanced dual

Berberine HCl Complex + cinnamon, bittermelon & gymnema 1300mg p/serving

Additional Information

Store in a cool, dry place.

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Metadata

Product Details

UPC / SKU8 50059 33800 1
DSLD Entry Date2024-07-25
Product TypeOther Combinations
FormCapsule
DSLD ID317001
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.