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5-HTP 100 mg

product on market Capsule Bluebonnet Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-Hydroxytryptophan serves as a precursor to serotonin and is researched for its role in supporting mood and sleep. There is moderate evidence suggesting its efficacy in managing certain psychological symptoms. The ingredient profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Cellulose Hypromellose Water, Purified Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one capsule daily, preferably on an empty stomach at bedtime or as directed by a healthcare practitioner.

Warnings & Precautions

Caution: Consult with your healthcare practitioner prior to use if you are taking prescription medication, particularly cognitive drugs, such as MAO inhibitors and selective serotonin reuptake inhibitors (SSRIs), or other anti-depressants medications.

May cause drowsiness, so refrain from operating machinery or driving a vehicle when taking this product.

Keep out of reach of children.

Formulation Notes

Bluebonnet’s 5-HTP 100 mg vegetable capsules are formulated to help support healthy weight management, mood, relaxation, and occasional sleeplessness with 5-hydroxytryptophan from Griffonia simplicifolia.

Guaranteed free of Peak-X

May support Occasional sleeplessness Brain & mood

Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans and sesame. Also free of gluten, barley, rice, sodium and sugar

Bluebonnet’s KOF-K Certification #K-0000700

Made with Non GMO ingredients

Mood & sleep support

Vegan

Gluten free

K Parve (Kosher)

Additional Information

K Parve (Kosher)

Store tightly closed in a cool, dry place.

Made with Non GMO Ingredients

Metadata

Product Details

UPC / SKU7 43715 00051 3
DSLD Entry Date2024-06-20
Product TypeAmino acid/Protein
FormCapsule
DSLD ID314982
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.