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Vein Supreme

product on market Capsule NOW Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains horse chestnut and butcher's broom, which have moderate evidence for supporting venous tone and reducing leg swelling. Grape seed extract and rutin are included for their antioxidant properties and vascular support. Overall, clinical evidence for this specific combination of ingredients remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Vein Supreme
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Veg Capsule(s)
Serving Size
45
Servings
Other Combinations
Product Type
20%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Trunorin
250 mg
Market median: 285.0mg (90 products) 1 studies — no high-quality reviews
Butcher's Broom extract
50 mg
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
10 mg
Market median: 500.0mg (19 products)

Other Ingredients

Rice Flour Hypromellose Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 2 capsules daily.

Warnings & Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Contains tree nut (horse chestnut).

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation Notes

NOW Vein Supreme is a combination of botanical ingredients for the support of healthy vascular function. Vein Supreme features Trunorin, a clinically tested extract of prickly ash bark, whose characteristic constituents have been found to promote normal venous function and integrity. Also included are butcher's broom and horse chestnut seed extract, both of which have long histories of use for the support of healthy veins.

Natural color variation may occur in this product.

Circulatory Support Supports Healthy Vein Function Supports Vascular Integrity

Vegetarian/Vegan

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients.

Additional Information

Store in a cool, dry place after opening.

GMP Quality Assured

Botanicals/Herbs Family owned since 1968.

Metadata

Product Details

UPC / SKU7 33739 03123 5
DSLD Entry Date2024-10-24
Product TypeOther Combinations
FormCapsule
BrandNOW
DSLD ID314206
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
9
Rct
2
Meta Analysis
2
Clinical Trial
1
Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023 PubMed DOI
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021 PubMed DOI
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011 PubMed DOI
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016 PubMed DOI
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021 PubMed DOI
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016 PubMed DOI
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009 PubMed DOI
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021 PubMed DOI
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition PubMed DOI
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies PubMed DOI
View all evidence for Grape Seed →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.