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Folic Acid

product on market Softgel Capsule BulkSupplements.com Safety: 60/100
60/100

Review before taking

  • Folic Acid: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Folic acid is a synthetic form of vitamin B9 used to support DNA synthesis and red blood cell formation, with strong evidence for preventing neural tube defects. Due to a safety score of 60, potential concerns regarding high-dose supplementation and masking vitamin B12 deficiency should be noted. Evidence coverage for this specific profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folic Acid: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of folic acid exceeds the recommended daily upper limit. The dosage is significantly higher than the maximum level generally considered safe for daily intake.

Label

Product Label

Label for Folic Acid
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
300
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1667 mcg DFE (417% DV)
Exceeds UL by 1667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)

Other Ingredients

Soybean Oil Gelatin Glycerin Water, Purified Beeswax
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take 1 softgel once daily, or as directed by a physician.

Warnings & Precautions

Allergen information: Soy

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation Notes

Free of: Dairy, yeast, gluten, sugars

Folic Acid 1000 mcg B9 vitamin Folic Acid 1mg Prenatal vitamins with folic acid

Prenatal vitamins with folic acid Folate supplement for women

Additional Information

Store in a dry, cool, dark place.

New

Metadata

Product Details

UPC / SKUX0033BXVAP
DSLD Entry Date2024-05-23
Product TypeVitamin
FormSoftgel Capsule
BrandBulkSupplements.com
DSLD ID313504
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
View all evidence for Folate →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.