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Candi-Free

product on market Tablet or Pill Akasha Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Berberine hydrochloride and extracts from Oregon grape and coptis root are researched for their potential to support glycemic control and metabolic health. There is moderate evidence supporting the efficacy of berberine in managing blood glucose levels. However, overall evidence coverage for this specific formulation remains very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Candi-Free
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
45
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
A Proprietary Extract Of
300 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Coptis Root, Rhizome Extract
30 mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Silica Stearic Acid Magnesium Stearate Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two tablets two times daily or as directed by your healthcare practitioner.

Warnings & Precautions

Notice: Do not use if you have or develop diarrhea, loose stools, or abdominal pain because rhubarb may worsen these conditions and be harmful to your health.

Warning: Do not use if pregnant or nursing. Caution: If taking medication including cyclosporin, consult your healthcare practitioner before use.

Keep out of the reach of children.

To report adverse events call 866-649-4334.

Formulation Notes

Candi-Free combines berberine hydrochloride, Oregon grape extract, and coptis root extract, with a proprietary extract of Chinese herbs - including ginger, licorice, and skullcap - to support detoxification of the liver and gallbladder, as well as healthy immune, detoxification, and elimination functions.

This product is Non-GMO, gluten free, and vegetarian.

This product is Non-GMO, gluten free, and vegetarian.

Concentrated Berberine formula for intestinal support

Metadata

Product Details

UPC / SKU7 55571 92912 9
DSLD Entry Date2024-09-25
Product TypeOther Combinations
FormTablet or Pill
BrandAkasha Naturals
DSLD ID313104
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.