🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Tablet(s) Serving Size
45 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 400mg
A Proprietary Extract Of
300 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 70mg
Coptis Root, Rhizome Extract
30 mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Silica Stearic Acid Magnesium Stearate Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take two tablets two times daily or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Notice: Do not use if you have or develop diarrhea, loose stools, or abdominal pain because rhubarb may worsen these conditions and be harmful to your health.

Warning: Do not use if pregnant or nursing. Caution: If taking medication including cyclosporin, consult your healthcare practitioner before use.

Keep out of the reach of children.

To report adverse events call 866-649-4334.

🧪 Formulation Notes

Candi-Free combines berberine hydrochloride, Oregon grape extract, and coptis root extract, with a proprietary extract of Chinese herbs - including ginger, licorice, and skullcap - to support detoxification of the liver and gallbladder, as well as healthy immune, detoxification, and elimination functions.

This product is Non-GMO, gluten free, and vegetarian.

This product is Non-GMO, gluten free, and vegetarian.

Concentrated Berberine formula for intestinal support

Product Details

UPC / SKU 7 55571 92912 9
DSLD Entry Date 2024-09-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 313104
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

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