Waterex

product on market Capsule GNC Total Lean 🟢 Safety: 100/100
Brand: GNC Total Lean
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
30 Servings
Botanical with Nutrients Product Type
38% Evidence Coverage

Supplement Facts — Evidence Check

25 mg (1471% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 25mg UL 100mg
25 mg (6% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 25mg
Corn, Powder
6.25 mg
Fennel, Powder
6.25 mg
6.25 mg
📊 Market median: 500.0mg (497 products) 📚 132 studies (Tier A: 0, B: 40)
This product: 6.25mg
Horsetail, Powder
6.25 mg
Parsley, Powder
6.25 mg
Uva Ursi Leaf Extract
6.25 mg

Other Ingredients

Microcrystalline Cellulose Gelatin Potassium Chloride Calcium Silicate Cellulose Magnesium Stearate Maltodextrin Silicon Dioxide Sodium Lauryl Sulfate

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take the contents of one pack daily. Do not take before bedtime.

Notice: Use in conjunction with the Total Lean Meal and Exercise Plan found on www.totallean.com

⚠️ Warnings & Precautions

Contains a bioengineered food ingredient.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition.

Warning: Cancer and reproductive Harm - www.p65warnings.ca.gov. Discontinue use two weeks prior to surgery. Do not take before bedtime.

Keep out of reach of children.

🧪 Formulation Notes

Scientifically formulated nutrition & weight management support system

Water balance with scientifically formulated Waterex

Gluten free, no milk.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you're not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days and we'll either refund your money or find a replacement product that is right for you.

Additional Information

30-day supply

Store in a cool, dry place.

For more information: 1-888-462-2548 GNC.com

Product Details

DSLD Entry Date 2024-07-25
Product Type Botanical with Nutrients
Form Capsule
Brand GNC Total Lean
Bundle Burn & Define Vitapak
DSLD ID 312258
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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