🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

3 Capsule(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 1000mg

Other Ingredients

Rice Bran Hypromellose Silica

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take 3 capsules daily, with or without food.

⚠️ Warnings & Precautions

Caution: Use only as directed.

If pregnant, nursing, taking medication, or under medical supervision for any condition, consult a healthcare professional before use.

Not intended for children. Keep out of reach of children.

Tamper evident. Do not use if printed safety seal under cap is broken or missing.

🧪 Formulation Notes

About Berberine HCL Berberine hydrochloride (HCl) is a bioactive alkaloid extracted from phellodendron plants. Among its many health benefits is activating the AMPK enzyme that helps regulate metabolism.

Berberine supports: Active metabolism Maintaining blood sugar, cholesterol, and triglyceride levels already within normal range Digestive and urinary health Immune system function

No milk, eggs, fish, crustacean shellfish, tree nuts, wheat, peanuts, soy, colors, flavors, preservatives, or magnesium stearate.

Supports cardiovascular, glucose metabolism & immune function

Vegetarian.

Gluten-Free.

Made in USA with globally sourced ingredients.

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 8 10034 44156 0
DSLD Entry Date 2024-08-22
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 310463
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

Compare Similar Products

View all Berberine products →