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5-HTP & Melatonin

product on market Capsule Swanson Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

L-5-Hydroxytryptophan and melatonin are used to support sleep and mood regulation. Research provides moderate evidence that melatonin aids sleep onset, while 5-HTP serves as a precursor to serotonin. The combination targets sleep quality and emotional balance through these distinct pathways.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP & Melatonin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veggie Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Rice Flour Hypromellose Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take one veggie capsule with water one-half hour before bedtime.

Warnings & Precautions

Warning: For adults only.

As melatonin may produce drowsiness, do not drive an automobile or operate heavy equipment after taking.

Do not take this product if you are pregnant or nursing, taking a prescription antidepressant, have an autoimmune condition or a depressive disorder, or are under 16 years of age. Consult your healthcare provider before use if you have a medical condition or if you are taking any prescription medications.

Do not take this product if you are pregnant or nursing, taking a prescription antidepressant, have an autoimmune condition or a depressive disorder, or are under 16 years of age. Keep out of reach of children.

Do not use if seal is broken.

Formulation Notes

Sleep support 2 in 1 formula

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 87614 02764 7
DSLD Entry Date2024-10-24
Product TypeOther Combinations
FormCapsule
BrandSwanson
DSLD ID308442
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.