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Osteo Bi-Flex Joint Health Triple Strength + MSM Formula

product on market Tablet or Pill Osteo Bi-Flex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine hydrochloride and Joint Shield 5-Loxin are used to support joint structure and function. Research provides moderate evidence that these ingredients may help manage joint discomfort. The overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo Bi-Flex Joint Health Triple Strength + MSM Formula
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
40
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
Sodium
20 mg (1% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
Market median: 1000.0mg (2 products)

Other Ingredients

Cellulose Silica Hydroxypropyl Methylcellulose Croscarmellose Cellulose Coating Titanium Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

2 Per day Directions for adult use: Take two (2) tablets per day preferably with food. As a reminder, discuss the supplements and medications you take with your health care providers.

Warnings & Precautions

Keep out of reach of children. Not intended for use by persons under the age of 18.

Caution: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Contains shellfish (crab, crayfish, lobster, shrimp) ingredients.

As a reminder, discuss the supplements and medications you take with your health care providers.

Formulation Notes

Range of Motion

During the day, you move your joints in so many different ways, getting up, sitting down, bending and flexing. Osteo Bi-Flex is America's #1 Joint Health Brand and supports joint comfort, so you can enjoy a range of motion for your day's activities. Source: IRI Total US - Multi Outlet: Latest 52 weeks ending April 25, 2021.

Osteo Bi-Flex Triple Strength + MSM contains glucosamine which helps to strengthen joints while helping maintain joint cartilage essential for comfortable movement. This formula also includes MSM which is vital in the support of connective tissue and healthy joints.

Osteo Bi-Flex is manufactured under the highest standards for product quality, purity and potency.

Made in the USA with select ingredients from around the world.

Osteo Bi-Flex Joint Health Triple Strength + MSM Formula Refers to level of Glucosamine HCI per tablet compared to regular strength. Shows improved joint comfort within 7 days! Based on two human studies with 5-LOXIN ADVANCED where subjects rated their joint health over time, subjects' joint health improved within 7 days, and continued to improve throughout the duration of the studies.

Glucosamine & MSM with joint shield

Free of Gluten Non-GMO

Additional Information

To learn more about Osteo Bi-Flex visit www.OsteoBiFlex.com or call us toll free 1-888-VITAHELP (848-2435).

Store at room temperature and avoid excessive heat, tamper resistant: Do not use if seal under cap is broken or missing.

Individual results may vary. #1 pharmacist recommended brand Based on the results of the Pharmacy Time Survey of Pharmacists' OTC Recommendations who recommend a "joint health" deny supplement, 2021-2022.

Metadata

Product Details

UPC / SKU0 30768 54127 9
DSLD Entry Date2024-03-22
Product TypeOther Combinations
FormTablet or Pill
DSLD ID307938
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.