🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
90 Servings
Amino acid/Protein Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

50 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 50mg

Other Ingredients

Microcrystalline Cellulose Hydroxypropylmethylcellulose Water Magnesium Stearate Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: Adults take 1 capsule once a day on an empty stomach or as directed by your qualified healthcare professional.

⚠️ Warnings & Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially if taking SSRIs, MAOs, or sedative medications) or have a medical condition; if adverse reactions occur, discontinue use.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially if taking SSRIs, MAOs, or sedative medications) or have a medical condition; if adverse reactions occur, discontinue use. Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Jarrow Formulas 5-HTP (5-Hydroxytryptophan) is an extract of Griffonia simplicifolia seeds from coastal West Africa. Purity is assured by HPLC. 5-HTP is the direct metabolic precursor to serotonin and is important for the production of melatonin, a hormone secreted by the pineal gland that aids biorhythm regulation.

Vegan

5-Hydroxytryptophan

Serotonin precursor Helps support a balanced mood

Non-GMO Gluten free

General wellness

No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.

Additional Information

Store in a cool, dry place.

Non GMO Project Verified nongmoproject.org

Product Details

UPC / SKU 7 90011 15044 2
DSLD Entry Date 2024-01-24
Product Type Amino acid/Protein
Form Capsule
DSLD ID 307545
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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