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5-HTP 200 mg

product on market Capsule Nature's Truth Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-Hydroxytryptophan is a precursor to serotonin used to support mood and sleep regulation. Research provides moderate evidence for its efficacy in managing depressive symptoms. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 200 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Quick Release Capsule(s)
Serving Size
25
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Rice, Powder Gelatin Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: for adults, take two (2) quick release capsules on an empty stomach as needed or at bedtime as 5-HTP may produce drowsiness. To reduce potential side effects such as nausea: (1) Take 5-HTP with food or 30 minutes after taking a meal. (2) Start with one (1) capsule daily for the first two weeks.

Warnings & Precautions

Warning: not intended for use by pregnant or nursing women. If you are taking any medications, including migraine medications or antidepressants such as MAO inhibitors (MAOIs) or Selective Serotonin Reuptake Inhibitors (SSRIs), consult your doctor before use.

If you have any medical condition, including mental health, nervous system, or gastrointestinal disorders, consult your doctor before use. If any adverse reactions occur, immediately stop using this product and consult your doctor. Do not drive, operate machinery or consume alcohol when taking this product. May cause mild gastrointestinal upset. If seal under cap is damaged or missing, do not use.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Formulation Notes

5-Hydroxytryptophan 5-HTP 200mg per serving

Gluten free Non GMO

No gluten, wheat, yeast, milk, lactose, soy, artificial color, artificial flavor, artificial sweetener, preservatives. Non-GMO

Supports a healthy mood

Our Non-GMO pledge please visit our website

Additional Information

100% Quality Satisfaction guarantee Vitamins

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU8 40093 10133 4
DSLD Entry Date2024-05-23
Product TypeAmino acid/Protein
FormCapsule
DSLD ID306608
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.