Acetyl L-Carnitine 500 mg by Carlson — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
100% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size

120 Servings

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Acetyl-L-Carnitine

500 mg

📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)

This product: 500mg

Other Ingredients

Hypromellose

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (88% of products) Nutrient (18% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Directions: Adults: Take one capsule one to three times daily or as directed by your health care provider.

⚠️ Warnings & Precautions

Warning: For adult use only.

Do not use if pregnant or lactating.

🧪 Formulation Notes

Free-form amino acid

Cognitive health Brain function Energy production

Acetyl L-Carnitine is a highly bioavailable form of L-Carnitine that can cross the blood-brain barrier. Acetyl L-Carnitine has an antioxidant effect that helps maintain healthy cellular energy metabolism and supports brain function. Acetyl L-Carnitine is a free-form amino acid that's important for cellular production and protein formation.

Gluten-free No artificial preservatives

Potency & quality guaranteed An FDA Regulated Facility

Additional Information

Carlson. Providing the highest quality nutritional supplements since 1965

Keep bottle tightly closed. Store away from heat and moisture.

Product Details

UPC / SKU 0 88395 07921 4

DSLD Entry Date 2023-12-14

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand Carlson

DSLD ID 304724

Data Updated 2026-04-11

Research Evidence

80 Research Sources

49 Avg Quality Score

43 Rct

14 Clinical Trial

11 Systematic Review

9 Meta Analysis

2 Regulatory Source

A Propionyl-L-carnitine for intermittent claudication

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI Cochrane

A Carnitine supplements for people with chronic kidney disease requiring dialysis

Systematic Review The Cochrane database of systematic reviews 2022

PubMed DOI Cochrane

A Acetyl-L-carnitine for patients with hepatic encephalopathy

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

B Carnitine for fatigue in multiple sclerosis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B L-carnitine for cognitive enhancement in people without cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

B Carnitine for fatigue in multiple sclerosis

Systematic Review The Cochrane database of systematic reviews 2010

PubMed DOI Cochrane

B Systematic Review and Meta-analysis on Effect of Carnitine, Coenzyme Q10 and Selenium on Pregnancy and Semen Parameters in Couples With Idiopathic Male Infertility

Meta Analysis Urology 2022

PubMed DOI

B Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis

Systematic Review Reproductive sciences (Thousand Oaks, Calif.) 2025

PubMed DOI

B Efficacy and Effectiveness of Carnitine Supplementation for Cancer-Related Fatigue: A Systematic Literature Review and Meta-Analysis

Meta Analysis Nutrients 2017

PubMed DOI

View all evidence for Carnitine →