Defend
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 71% of ingredients have research evidence
A
Label Compliance Grade
Product Label
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Label Data
4 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
71%
Evidence Coverage
Supplement Facts — Evidence Check
1 Gram(s)
📊 Market median: 250.0mg (562 products)
📚 53 studies (Tier A: 0, B: 19)
600 mg
📊 Market median: 600.0mg (7 products)
📚 39 studies (Tier A: 2, B: 13)
500 mg
📊 Market median: 60.0mg (107 products)
📚 1 studies — no high-quality reviews
250 mg
📊 Market median: 320.0mg (426 products)
📚 24 studies (Tier A: 0, B: 5)
📊 Market median: 4002.0mg (1 products)
📚 20 studies (Tier A: 0, B: 2)
Red Clover Flower Extract
200 mg
150 mg
📊 Market median: 333.0mg (166 products)
📚 9 studies (Tier A: 0, B: 2)
Other Ingredients
Gelatin
Rice Flour
Magnesium Stearate
Silicon Dioxide
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (83% of products)
Nutrient (4% of products)
Target Groups
Adult (18 - 50 Years)
Women (not pregnant or lactating)
Product Information
📋 Directions for Use
Suggested use: As a dietary supplement, take four (4) capsules with 8-12 fl oz of water.
⚠️ Warnings & Precautions
Warning: For use by healthy adults only, not recommended for persons under the age of 18.
Do not use if you are pregnant or nursing.
Seek advice from a healthcare professional before taking if you have any preexisting medical condition to ensure it is safe to take this product. In case of accidental overdose, contact a poison control center immediately.
Keep out of the reach of children.
🧪 Formulation Notes
Powerful on cycle support Total organ protection Supports healthy lipids
Additional Information
Made in USA GMP Good Manufacturing Practice
Product Details
UPC / SKU
7 28614 77849 7
DSLD Entry Date
2023-12-14
Product Type
Other Combinations
Form
Capsule
Brand
Huge Nutrition
DSLD ID
299800
Data Updated
2026-04-11
Research Evidence
69
Research Sources
55
Avg Quality Score
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A
Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
B
Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
B
Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
B
Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
B
Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
B
Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
B
Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
B
The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
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