🟡 60/100

Review before taking

  • Vitamin D3: 0.25mg is 2.5× the Tolerable Upper Intake Level (0.1mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

Vitamin D3 is supported by strong evidence for maintaining bone health and supporting immune function. However, the high dosage of 10,000 IU may pose safety concerns regarding toxicity or hypercalcemia in some users. This high potency requires careful consideration of individual tolerance and safety.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Safety Alerts

⚠️ Vitamin D3: 0.25mg is 2.5× the Tolerable Upper Intake Level (0.1mg)

This product received a low safety score because the amount of Vitamin D3 exceeds the recommended daily upper limit. Specifically, it provides 2.5 times the maximum amount considered safe for daily intake.

Label Data

1 Softgel(s) Serving Size
60 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

250 mcg (1250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.5× (UL: 0.1 mg) 📚 608 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.25mg UL 0.1mg

Other Ingredients

Olive Oil Gelatin Glycerin Water, Purified

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Adult (18 - 50 Years) No Allergies Gluten Free

Product Information

📋 Directions for Use

Directions: For adults, one softgel daily, or as directed by your health practitioner. Do not exceed one softgel per day.

⚠️ Warnings & Precautions

Warning: For adult use only.

Do not exceed recommended serving. Consult your health care practitioner prior to use if you have a medical condition, if you have kidney disorder or hypercalcemia, if you are taking prescription medication, or if you are pregnant or nursing.

Consult your health care practitioner prior to use if you have a medical condition, if you have kidney disorder or hypercalcemia, if you are taking prescription medication, or if you are pregnant or nursing.

Keep out of reach of children.

🧪 Formulation Notes

Research suggests that Vitamin D may be your single most important supplemental nutrient. Required for optimal calcium absorption, Vitamin D promotes strong bones and is vital support for a healthy immune system. Vitamin D is obtained from the diet or from sun exposure. However, vitamin D is not abundant in foods and people are increasingly avoiding the sun. This high-potency supplementation is necessary to ensure healthy levels of this key nutrient.

Bone & immune support

Free from artificial colors and artificial preservatives. Free from all of the major allergens identified in the U.S. Food Allergen Labeling and Consumer Protection Act.

Gluten free

Additional Information

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 01048 2
DSLD Entry Date 2023-10-24
Product Type Vitamin
Form Softgel Capsule
Brand NaturesPlus
DSLD ID 298550
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
View all evidence for Vitamin D →

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