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Melatonin Extended Release 2.5 mg

product on market Tablet or Pill Kirkman Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Melatonin is supported by strong evidence for its role in regulating sleep-wake cycles and improving sleep onset. Calcium is a fundamental mineral essential for bone health and neuromuscular function. Research for these ingredients is extensive, though the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin Extended Release 2.5 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
150
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
132 mg (10% DV)
2.5 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Microcrystalline Cellulose Water, Purified Stearic Acid Citric Acid Silicon Dioxide Sodium Glycolate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Tablets may be swallowed with foods like applesauce, mashed potatoes, or peanut butter followed by water.

Suggested Use: Swallow one tablet one hour before bedtime or as directed by a physician.

Warnings & Precautions

Keep out of the reach of children.

Tablets must be swallowed whole. Do not crush or dissolve in liquids as this will destroy the extended release system that extends dissolve time.

Caution: Formulated for adults and children four years and older. for children under four, consult a physician.

Formulation Notes

Individual tablets may darken over time but the potency and efficacy is not affected.

Free of: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame

Gluten-free

Promotes sleep with slow release

Additional Information

Important: Store in a cool dry place and tightly capped.

Ultra Tested cGMP

Metadata

Product Details

UPC / SKU8 12325 02119 2
DSLD Entry Date2023-10-24
Product TypeOther Combinations
FormTablet or Pill
BrandKirkman
DSLD ID297227
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Melatonin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.