🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Enteric Coated Caplet(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 200.0mg (52 products) 📚 10 studies (Tier A: 0, B: 6)
This product: 400mg

Other Ingredients

Dicalcium Phosphate Cellulose Stearic Acid Croscarmellose Magnesium Stearate Silica Cellulose Triacetin Propylene Glycol Methacrylic Acid Titanium Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (83% of products) Nutrient (6% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement for adults, take one (1) enteric coated caplet one to three times daily on an empty stomach at least 30 minutes prior to meals.

⚠️ Warnings & Precautions

Caution: If you are pregnant, nursing a baby or considering becoming pregnant, ask a doctor before using this product. If you take a prescription medication or have any medical condition, consult a physician before using this product.

If any adverse reactions occur, immediately stop using this product and consult your doctor. Do not eat freshness packet. Keep packet in bottle until all product has been consumed. If seal under cap is damaged or missing, do not use.

Keep out of reach of children.

🧪 Formulation Notes

Enteric coated

General health

Supports joint health Supports mood & emotional well-being

SAM-e is a compound that is formed naturally in the body from the amino acid methionine. However, various factors, such as age and diet, can cause levels of SAM-e to fluctuate or decline.

Meijer 400 mg SAM-e caplets have an enteric coating that optimizes absorption to help support joint health and emotional well being.

Supports healthy mood and joint comfort

No wheat, soy, dairy, artificial flavors, preservatives, gluten, artificial sweetener, fish, lactose.

GF Gluten free

Additional Information

Our quality guarantee www.mejer.com/satisfaction The Meijer Family

Do not eat freshness packet. Keep packet in bottle until all product has been consumed.

Store at room temperature (59 degrees F-86 degrees F) (15 degrees C-30 degrees C).

Product Details

DSLD Entry Date 2023-08-23
Product Type Non-Nutrient/Non-Botanical
Form Other (e.g. tea bag)
Brand Meijer
DSLD ID 296595
Data Updated 2026-04-11

Research Evidence

12 Research Sources
58 Avg Quality Score
8 Meta Analysis
3 Systematic Review
1 Rct
B S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2006
B S-adenosyl methionine (SAMe) for depression in adults
Meta Analysis The Cochrane database of systematic reviews 2016
B Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease
Meta Analysis Annals of the rheumatic diseases 2024
B SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis
Meta Analysis American journal of cardiovascular drugs : drugs, devices, and other interventions 2024
B S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis
Meta Analysis General hospital psychiatry 2024
B S-adenosyl-L-methionine for alcoholic liver diseases
Systematic Review The Cochrane database of systematic reviews 2001
B WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2015
C S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis
Meta Analysis PloS one 2015
C S-Adenosylmethionine (SAMe) for Liver Health: A Systematic Review
Systematic Review Nutrients 2024
C SAMe-TT2R2 to Predict Clinical Outcomes and Time in Therapeutic Range in Patients on Vitamin K Antagonists: A Systematic Review and Meta-Analysis
Meta Analysis The Annals of pharmacotherapy 2024
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