L-Carnitine by Metagenics — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
100% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size

30 Servings

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

L-Carnitine

500 mg

📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)

This product: 500mg

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Magnesium Stearate Silica

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (88% of products) Nutrient (18% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take one capsule daily or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Caution: If pregnant or nursing consult your healthcare practitioner before use.

Keep out of the reach of children.

Practitioner exclusive

🧪 Formulation Notes

L-Carnitine plays a role in free fatty acid metabolism and metabolic health and is required for the breakdown of fats and glucose into energy. Decreased levels of L-carnitine have been observed during pregnancy, supplementation has been shown to help improve plasma levels.

This product is non-GMO, gluten-free, and vegetarian

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Support for fat metabolism

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Product Details

UPC / SKU 7 55571 95333 9

DSLD Entry Date 2023-09-25

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand Metagenics

DSLD ID 295756

Data Updated 2026-04-11

Research Evidence

80 Research Sources

49 Avg Quality Score

43 Rct

14 Clinical Trial

11 Systematic Review

9 Meta Analysis

2 Regulatory Source

A Propionyl-L-carnitine for intermittent claudication

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI Cochrane

A Carnitine supplements for people with chronic kidney disease requiring dialysis

Systematic Review The Cochrane database of systematic reviews 2022

PubMed DOI Cochrane

A Acetyl-L-carnitine for patients with hepatic encephalopathy

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

B Carnitine for fatigue in multiple sclerosis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B L-carnitine for cognitive enhancement in people without cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

B Carnitine for fatigue in multiple sclerosis

Systematic Review The Cochrane database of systematic reviews 2010

PubMed DOI Cochrane

B Systematic Review and Meta-analysis on Effect of Carnitine, Coenzyme Q10 and Selenium on Pregnancy and Semen Parameters in Couples With Idiopathic Male Infertility

Meta Analysis Urology 2022

PubMed DOI

B Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis

Systematic Review Reproductive sciences (Thousand Oaks, Calif.) 2025

PubMed DOI

B Efficacy and Effectiveness of Carnitine Supplementation for Cancer-Related Fatigue: A Systematic Literature Review and Meta-Analysis

Meta Analysis Nutrients 2017

PubMed DOI

View all evidence for Carnitine →