Bone Builder Extra Strength by Metagenics — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
25% of ingredients have research evidence

B Label Compliance Grade

Product Label

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Label Data

3 Tablet(s) Serving Size

30 Servings

Mineral Product Type

25% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates

1 Gram(s) (1% DV)

Calcium

1010 mg (78% DV)

Phosphorus

520 mg (42% DV)

✅ Within RDA (0.7× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 520mg UL 4000mg

Microcrystalline Hydroxyapatite Concentrate

3 Gram(s)

Other Ingredients

Microcrystalline Cellulose Stearic Acid Cellulose Croscarmellose Sodium Silica Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take three tablets once daily or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Caution: If pregnant, nursing, or taking medication, consult your healthcare practitioner before use.

Keep out of reach of children.

Tamper evident: Do not use if safety seal is missing or broken.

Practitioner exclusive

🧪 Formulation Notes

Bone Builder Extra Strength provides bone health support with microcrystalline hydroxyapatite concentrate (MCHC), a highly absorbable crystalline compound comprised of naturally-occurring components of bone which is backed by over 30 years of research. MCHC contains naturally occurring calcium, phosphorus and trace amounts of other minerals, bone growth factors, and collagen and other vital bone proteins. Each serving of just three tablets provides over 1,000 mg of calcium.

This product is non-GMO and gluten free.

Enhanced bone support

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Non GMO Project Verified nongmoproject.org Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Product Details

UPC / SKU 7 55571 01310 1

DSLD Entry Date 2023-08-23

Product Type Mineral

Form Tablet or Pill

Brand Metagenics

DSLD ID 295637

Data Updated 2026-04-11

Research Evidence

849 Research Sources

56 Avg Quality Score

450 Meta Analysis

152 Rct

137 Systematic Review

73 Clinical Trial

11 Regulatory Source

7 Other

7 Guideline

3 Openfda Safety

2 Cochrane Review

2 Observational

A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)

Meta Analysis The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life

Meta Analysis The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps

Systematic Review The Cochrane database of systematic reviews 2008

PubMed DOI Cochrane

A Calcium and vitamin D for increasing bone mineral density in premenopausal women

Systematic Review The Cochrane database of systematic reviews 2023

PubMed DOI Cochrane

A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019

PubMed DOI

A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021

PubMed DOI

A Calcium channel blockers versus other classes of drugs for hypertension

Systematic Review The Cochrane database of systematic reviews 2021

PubMed DOI

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