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Melatonin CR

product on market Tablet or Pill XYMOGEN Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Melatonin is supported by strong evidence for managing sleep onset and circadian rhythm disruptions. Vitamin B6 and calcium act as cofactors in the synthesis of neurotransmitters involved in sleep regulation. Research indicates these ingredients are generally safe for short-term use when taken as directed.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin CR
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
180
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Calcium
35 mg (3% DV)
5 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Methylcellulose Hydroxypropyl Cellulose Ascorbyl Palmitate Silica Tapioca Maltodextrin Sunflower Lecithin Palm Oil Guar Gum
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one tablet with water 20 minutes before bedtime, or as directed by your healthcare professional.

Warnings & Precautions

Professional use only Not for resale on third-party websites, including, but not limited to, Amazon and eBay.

Consult your healthcare professional prior to use.

Individuals taking medication should discuss potential interactions with their healthcare professional.

Do not use if tamper seal is damaged.

Cautions: Not for use by children under 12 years of age.

Do not take when operating machinery or driving a vehicle.

Storage: Keep closed in a cool, dry place out of reach of children.

Formulation Notes

Melatonin CR is a vegetarian formula with a biphasic delivery system that releases melatonin quickly and then steadily.

Melatonin CR is a vegetarian formula with a biphasic delivery system that releases melatonin quickly and then steadily. Melatonin is naturally produced in the pineal gland in response to changes in light exposure; it helps promote healthy sleep patterns as well as antioxidant and immune activities. Melatonin CR can support these functions by helping to maintain normal levels of melatonin in the body.

Formulated to exclude: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

Biphasic controlled-release melatonin formula

Additional Information

Storage: Keep closed in a cool, dry place out of reach of children.

ePV (ePedigree Verification)

GMP Compliant Third-Party Verified

Scan to learn more! This package is completely recyclable

Metadata

Product Details

UPC / SKU8 71149 00289 3
DSLD Entry Date2023-07-18
Product TypeOther Combinations
FormTablet or Pill
BrandXYMOGEN
DSLD ID294757
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Melatonin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.