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Melatonin 20 mg

product on market Capsule Pure Encapsulations Safety: 60/100
60/100

Review before taking

  • Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is a hormone used to regulate sleep-wake cycles, with moderate evidence supporting its use for sleep onset. However, the 20 mg dosage is significantly higher than standard physiological levels. This high concentration may increase the risk of side effects, contributing to a lower safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a lower safety score because it contains 20mg of melatonin, which is twice the recommended upper limit of 10mg.

Label

Product Label

Label for Melatonin 20 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
180
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg
Exceeds UL by 2.0× (UL: 10 mg) 240 studies (A:2, B:109)

Other Ingredients

Plant Fiber Cellulose Water
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: As a dietary supplement, take 1 capsule daily, 30-60 minutes before bedtime.

Warnings & Precautions

Keep out of the reach of children.

Use only if safety seal is intact.

Warning: This product is not intended for sleep support.

Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. This product may be contraindicated for individuals taking corticosteroids.

Do not drive or operate machinery when taking melatonin.

Formulation Notes

Certified gluten free by the Gluten-Free Certification Organization, www.gluten.org

Promotes healthy cells and tissues

Gluten-free, non GMO & hypoallergenic

Gluten-free, non GMO & hypoallergenic

Additional Information

Store in a cool, dry place.

Warning: See side panel.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 66298 00812 7
DSLD Entry Date2023-07-18
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID294021
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Melatonin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.