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5-HTP 100 mg

product on market Capsule Basic Vitamins Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

L-5-Hydroxytryptophan serves as a precursor to serotonin and is researched for its role in supporting mood and sleep. There is moderate evidence suggesting its efficacy in managing depressive symptoms. However, overall evidence coverage for this specific formulation remains very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Microcrystalline Cellulose Gelatin Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one (1) capsule daily or as directed by your healthcare practitioner.

Warnings & Precautions

Keep out of the reach of children.

Do not use if inner seal is missing or broken.

Warning: Pregnant or lactating women, diabetics, hypoglycemics, individuals under the age of 18, people with known medical conditions and/or taking drugs (including prescription medications such as antidepressants SSIs, MAO inhibitors or sedatives) should consult with a licensed physician and/or pharmacist prior to taking this product.

Warning: Pregnant or lactating women, diabetics, hypoglycemics, individuals under the age of 18, people with known medical conditions and/or taking drugs (including prescription medications such as antidepressants SSIs, MAO inhibitors or sedatives) should consult with a licensed physician and/or pharmacist prior to taking this product.

May cause drowsiness.

Formulation Notes

Promotes a calm and relaxed mood

Gluten free

Contains No: Sugar, yeast, salt, wheat, gluten, corn, dairy products, artificial colors or preservatives.

Additional Information

Store at room temperature.

Basic's

Metadata

Product Details

UPC / SKU3 07610 60512 1
DSLD Entry Date2023-07-18
Product TypeAmino acid/Protein
FormCapsule
BrandBasic Vitamins
DSLD ID292239
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.