Extra Strength Glucosamine Chondroitin Complex by Nature's Bounty — Ingredients, Evidence & Safety

Product Label

Label for Extra Strength Glucosamine Chondroitin Complex

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Label Data

3 Tablet(s) Serving Size

40 Servings

Other Combinations Product Type

17% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 {Calories}

Total Carbohydrates

3 Gram(s) (1% DV)

Vitamin C

500 mg (833% DV)

Manganese

5 mg (250% DV)

✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 5mg UL 11mg

Sodium

45 mg (2% DV)

Glucosamine Chondroitin Complex

3000 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 3000mg

Other Ingredients

Vegetable Cellulose Contains Less Than 2% of

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

DIRECTIONS: For adults, take three (3) tablets daily, preferably one (1) tablet with each meal.

⚠️ Warnings & Precautions

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

WARNING: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

🧪 Formulation Notes

No Artificial Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast.

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Additional Information

Joint health is affected by many factors including heredity, gender, sports activities and weight. Both Glucosamine Sulfate and Chondroitin Sulfate are key structural components in cartilage. Extra Strength Glucosamine Chondroitin Complex plays an important role in the maintenance of joint cartilage. Extra Strength Glucosamine Chondroitin Complex also contains Vitamin C for collagen formation and Manganese, a mineral necessary for normal skeletal development. Individual results may vary.

Nutrition Questions or Comments? Call 1-800-433-2990 Mon. - Sat . 9 AM - 7 PM ET

LABORATORY TESTED GUARANTEED QUALITY

NATURE'S BOUNTY(R)

Prod. No. 4963 10F B17215

Supports Comfortable Movement

COATED FOR EASY SWALLOWING Supports Joint Health

Store at room temperature.

Product Details

UPC / SKU 0 74312 04963 7

DSLD Entry Date 2014-01-24

Product Type Other Combinations

Form Tablet or Pill

Brand Nature's Bounty

DSLD ID 29207

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →