🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Softgel(s) Serving Size
60 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

5000 mcg (16667% DV)
📊 166.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 5.0mg

Other Ingredients

Soybean Oil Gelatin Glycerin yellow Beeswax Water Rapeseed Lecithin Carmine

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (91% of products) Nutrient (57% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Adults, consult your physician before use. Take one softgel daily, with water and a meal.

⚠️ Warnings & Precautions

Store tightly closed, in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing. Caution: Do not exceed 1 softgel daily unless recommended by your physician.

Biotin may interfere with lab tests. If you are taking medication or planning to undergo lab testing, consult your physician before use.

🧪 Formulation Notes

May help support healthy hair, skin and nails For those diagnosed with very low levels of biotin Maximum 5,000 mcg - For adults deficient in biotin, as diagnosed by their physician using appropriate biomarkers.

No synthetic dyes - colors derived from natural sources No artificial flavors Gluten free

USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org

Additional Information

#1 pharmacist recommended vitamin & supplement brand Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.

USP Verified Dietary Supplement

Everyday Value

Store tightly closed, in a cool, dry place, out of reach of children.

Product Details

UPC / SKU 0 31604 03171 8
DSLD Entry Date 2023-06-22
Product Type Vitamin
Form Softgel Capsule
Brand Nature Made
DSLD ID 287808
Data Updated 2026-04-11

Research Evidence

31 Research Sources
53 Avg Quality Score
12 Meta Analysis
9 Systematic Review
5 Rct
2 Clinical Trial
1 Regulatory Source
1 Openfda Safety
B Pentasaccharides for the treatment of deep vein thrombosis
Meta Analysis The Cochrane database of systematic reviews 2017
B Quantitative comparison of the efficacy of clinical drug treatments for primary progressive multiple sclerosis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2023
B Dietary interventions for multiple sclerosis-related outcomes
Meta Analysis The Cochrane database of systematic reviews 2020
B Interventions for infantile seborrhoeic dermatitis (including cradle cap)
Meta Analysis The Cochrane database of systematic reviews 2019
B Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis
Meta Analysis Fertility and sterility 2021
B Effect of feeding biotin on milk production and hoof health in lactating dairy cows: a quantitative assessment
Meta Analysis Journal of dairy science 2011
B Factitious Graves' Disease Due to Biotin Immunoassay Interference-A Case and Review of the Literature
Systematic Review The Journal of clinical endocrinology and metabolism 2016
B Effect of biotin on milk performance of dairy cattle: a meta-analysis
Meta Analysis Journal of dairy science 2011
B PROVIT: Supplementary Probiotic Treatment and Vitamin B7 in Depression-A Randomized Controlled Trial
Rct Nutrients 2020
B High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials
Meta Analysis Multiple sclerosis and related disorders 2021
View all evidence for Biotin →

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