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Melatonin 5 mg Time Release

product on market Tablet or Pill Natrol Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is supported by strong evidence for its role in regulating sleep-wake cycles and reducing sleep onset latency. Vitamin B6 serves as a cofactor in the synthesis of neurotransmitters that influence sleep. Together, these ingredients target sleep quality and duration, though individual responses to the 5 mg dosage may vary.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin 5 mg Time Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
250
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (590% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
5 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Microcrystalline Cellulose Dicalcium Phosphate Methylcellulose Magnesium Stearate Stearic Acid Hypromellose Silicon Dioxide Glycerin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1 tablet 20 minutes before bedtime.

Warnings & Precautions

Keep out of reach of children.

Warning: You may experience some residual drowsiness.

If you are under medical supervision or using any tranquilizers or sedatives, see the advice of your healthcare professional prior to using. Consult your healthcare professional prior to use if you have an autoimmune condition, depressive disorder or are pregnant or lactating.

Not for use by children under 12 years of age.

Do not take when operating machinery or driving a vehicle.

Formulation Notes

Natrol Melatonin 5mg Time Release: 2-layer table-outer layer releases Melatonin quickly to help you fall asleep faster, followed by the controlled release of an inner layer to help you sleep through the night Contains vitamin B-6 to support the body's natural production of Melatonin

Helps establish normal sleep patterns 100% drug-free and non-habit forming

100% drug-free and non-habit forming

Melatonin is a nighttime sleep aid for occasional sleeplessness.

Sleep Time Release Fall asleep faster, stay asleep longer

100% Drug-free

Vegetarian

No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, yeast, artificial colors or flavors, added sugar or preservatives

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 47469 07417 3
DSLD Entry Date2023-06-22
Product TypeOther Combinations
FormTablet or Pill
BrandNatrol
DSLD ID287520
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.