🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
120 Servings
Amino acid/Protein Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

100 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg

Other Ingredients

Gelatin Rice Flour

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommended Use: Take 1 serving (1 capsule) with water or your favorite beverage twice daily on an empty stomach or with food. Take first dose in the morning and second dose mid-day or evening depending on preference.

⚠️ Warnings & Precautions

Warning: Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.

Do not use if seal is broken.

🧪 Formulation Notes

Support healthy serotonin levels & enhanced mood

5-Hydroxytryptophan (5-HTP) is a chemical that the body makes from tryptophan, an essential amino acid that you get from the diet. After tryptophan is converted into 5-HTP, the chemical is then changed into another chemical called serotonin, a neurotransmitter, which relays signals between brain cells.

Enhance sleep & reduce appetite

Serotonin helps regulate mood and behavior, meaning 5-HTP may have a positive effect on sleep, mood, anxiety, appetite, and pain sensation. Some doctors consider 5-HTP to be the best natural appetite suppressant. 5-HTP is the immediate nutrient precursor to the neurotransmitter serotonin, also known as 5-HT (5-hydroxytryptamine). Serotonin has many profoundly important functions including a role in sleep, appetite, memory, learning, temperature regulation, mood, sexual behavior, cardiovascular function, muscle contraction, and endocrine regulation.

5-HTP is not found in the foods we eat, although tryptophan is. Eating foods with tryptophan does not significantly increase 6-HTP levels.

High-Performance Liquid Chromatography (HPLC) Verified

Mental performance

Ultra pure ingredients

Ultra micronized Max bioavailability

Improves well-being Support healthy serotonin levels Reduce stress & anxiety Improve brain function

Pharmaceutical grade

Increase sense of well-being Suppress appetite Reduce stress & anxiety Enhance sleep cycle Improve brain function Boost energy levels

Additional Information

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Made in the USA

Pure nutrition Go green

Product Details

UPC / SKU 8 20103 30974 5
DSLD Entry Date 2023-06-22
Product Type Amino acid/Protein
Form Capsule
DSLD ID 287378
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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